Autoimmune

?

Joslin11:
I'm 52, female, have some (10-12) blotches that have suddenly appeared on my legs - front and back. They are like a ring, not perfect, some irregular, and are darker at the edge with a weakening of color toward the center, almost like a faded bruise, or a washed out water color circle. They are red, darker on the outside, fading some toward the middle. Most are about the size of a penny to a quarter. Some are more oval. They do not itch. They are not raised. They seem to be getting bigger and more plentiful. I have had them for about a month. I am not in great health, have acute intermittant porphyria (they are NOT from my porphyria) and high blood pressure. I thought they looked like ring worm, but was told they are not. I am suspicious they are vascular in nature, and am worried they are a sign somehow of worsening health. Thank you.  4-18-05

I'm afraid I can't tell from your description just what you have. "Ringworm" (fungus) is scaly, so that seems unlikely. These spots don't sound like eczema or infection either. They also don't remind me of any systemic diseases. I think you need to see a skin doctor, who may recommend a skin biopsy to see what's going on. For me to say anything else at this point would just be guesswork.

Take care.

Dr. Rockoff

 
porphyria?

This is a metabolic problem that is thought to be hereditary; however, it could also be chemically induced.

 

"Some chemically-injured patients with Multiple Chemical Sensitivity (MCS) show disturbances in their body's system for making heme, which is the primary component of hemoglobin in red blood cells. Their lab tests reveal abnormal activity in one or more of the eight enzymes involved in heme production. Since most heme is made in the bone marrow, these "disorders of porphyrin metabolism" are usually found there or in the liver. They can have a disruptive effect on numerous processes that rely on heme and hemoglobin. Of clear concern to MCS patients are the "cytochrome P450" enzyme system, which uses heme to detoxify chemicals in the liver and other vital organs, and the oxygen transport system, which relies on hemoglobin to carry oxygen from the lungs to other body organs."

 

From liver foundation.org the following:


"Porphyrins are chemical compounds that are stepping stones along the pathway which leads to the formation of heme in humans, and to chlorophyll in plants. They are responsible for the fact that "blood is red, and grass is green." Heme is essential if the body is to work properly."

"In porphyria, the cells do no convert porphyrins to heme in a normal manner. Because of this, porphyrins build up in the body and are excreted in the urine and stool in excessive amounts."
 
"Porphyria is a group of different disorders caused by abnormalities in the chemical steps leading to the production of heme, a substance that is important in the body. The largest amounts of heme are in the blood and bone marrow, where it carries oxygen. Heme is also found in the liver and other tissues."

"Multiple enzymes are needed for the body to produce heme. If any one of the enzymes is abnormal, the process cannot continue and the intermediate products, porphyrin or its precursors, may build up and be excreted in the urine and stool."

"The porphyria disorders can be grouped by symptoms—whether they affect the skin or the nervous system. The cutaneous porphyrias affect the skin. People with cutaneous porphyria develop blisters, itching, and swelling of their skin when it is exposed to sunlight. The acute porphyrias affect the nervous system. Symptoms of acute porphyria include pain in the chest, abdomen, limbs, or back; muscle numbness, tingling, paralysis, or cramping; vomiting; constipation; and personality changes or mental disorders. These symptoms appear intermittently."  

Source

AND   


I would suspect that this is an autoimmune situation.  I also suspect that it is something that 2-butoxyethanol overexposure could cause.  Many things that are thought to be hereditary, are actually birth defects (late-occurring) from a parent or parents or grandparents who are chemically poisoned by such a chemical as this which is a teratogen (Harms the developing fetus) 
http://home.gci.net/~blessing/pages/inherited.htm

Do you or either of your parents have Chronic Fatigue Syndrome symptoms?  I suspect this chemical for causing such, more acurately for causing CFIDS.  For causing 'gulf war syndrome' and many birth defects & cancers.  First and foremost the underlying problem is the immune system becomes autoimmune.  Stop this & your body can heal itself.  That's what I think
A lady with Rheumatoid arthritis had exposure to this chemical in 1989 had her doctor concerned about the red blotches on the palms of her hands.  He said, "That is indicative of a liver problem, but your liver test says you are OK there"
 
Well, this chemical poisoning that she had which most likely caused the arthritis is one which fools the blood tests.  Autoimmune hemolytic anemia (which is always there with acute, direct exposure) fools the blood tests.  Doctors will need to check for that anyway when they find blood in urine ... and they should also find that the red blood cells are dying off prematurely.  That they are IMMATURE.  This fools the liver test because when too many red blood cells are immature it causes an elevated liver count.  But when the liver is not doing well, the counts go down.  (White blood cell counts will be more elevated than they really are, etc.  The computer read is not right; it has to be adjusted)
 
I don't have any medical background; however, I have looked into what 2-butoxyethanol does.  It harms the CNS; it harms the immune system; the skin; the pituitary gland & other organs - many, many things.  valdezlink.com/acute.htm
 

medhelp.org/perl6/dermatology/messages/33585.html

Here are some red blotches on a hand
http://ncchem.com/safe-arbor/pct.jpg  Porphyria cutanea tarda

 photo - fair use

These would be a part of what could come in 'the package' of 2-butoxyethanol poisoning.   

If 2-butoxyethanol were involved there would be autoimmune hemolytic anemia evidenced by red blood cells that are mostly immature & in the early years, trace blood in urine.  Check 'retic' rate & track it over time.

What about it being an EDC?

 

Some Thoughts on Cancers

... died of lung cancer?  It's too bad when someone gets lung cancer that cigarette smoking either directly or indirectly is suspected.  Several people in our town have died of 'lung cancer' and I note that they had exposure to 2-butoxyethanol.  One had tumors also in the brain; another had hemorrhaging after having 'beaten' lung cancer; another had 4 types of cancer:  lung, lymph, bone and liver.  All the kinds of thing this chemical would do.

The type of cancer Robert Urich had was a rare cancer of the joints that was known to sometimes spread to the lungs.

Was it Dioxin or the 2-butoxyethanol in jet fuel that cause this harm to the Vietnam Vet?

These theories are that of an ordinary person who looked into the harm of 2-butoxyethanol because someone in her family was harmed by it.

Its harm is unrecognized, but provable, if doctors should take an interest in checking into it.  Check out those with CFS, CFIDS, 'gulf war syndrome'

This chemical is a teratogen

This chemical, I believe, has been harming people since its invention in the 1930s.  - Sssso why did it showed up so much in the first gulf war?

Margaret's e-mail

Any help here?  *  or *  A study? *

Or is it just a doom 'n gloom story?  

Consider the Middle Ages and the "bubonic plaque."  

The bacteria was found to enter through the eyes.

Do you have any of these health ailments? X

  Immunuglobulin?   hemoglobinuria

4-22-05